SARS-CoV-2 vaccines are not free of neurological side effects.

SOURCE: Wiley Online Library

With interest, we read the article by Lu et al. about a systematic review of published neurological adverse reactions to SARS-CoV-2 vaccines.1 Included were 48 articles, and it was concluded that no severe neurological adverse reactions to any of the currently available SARS-CoV-2 vaccines have been reported.1 The review is appealing but raises the following comments and concerns.

We disagree with the conclusions that SARS-CoV-2 vaccines do not trigger neurological adverse reactions. Though rare, mild and severe neurological side effects have been occasionally reported.2 Search platforms and data bases to detect scientific reports about neurological adverse events may not be particularly helpful and do not provide many hits, but thorough assessments of various publications and their reference lists may help to find appropriate publications. Data from the mRNA vaccine clinical trials showed that 7 cases out of 37,000 vaccine recipients developed Bell's palsy.

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